Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

20% of Patients with Psoriasis Found to Have PsA

J Am Acad Dermatol; ePub 2018 Jun 18; Alinaghi, et al

1 in 5 patients with psoriasis have psoriatic arthritis (PsA), according to a recent review and meta-analysis, and with the growing recognition of ClASsification criteria for Psoriatic ARthritis (CASPAR), more homogenous and comparable prevalence estimates are expected to be reported. 2 authors independently searched 3 databases for studies reporting on the prevalence or incidence of PsA in patients with psoriasis. A proportion meta-analysis was performed to calculate the pooled proportion estimates of PsA in patients with psoriasis. They found:

  • A total of 266 studies were included, examining 976,408 patients with psoriasis.
  • Overall, the pooled proportion of PsA among patients with psoriasis was 19.7% (18.5%-20.9%).
  • In children and adolescents (<18 years), the pooled prevalence was 3.3% (2.1%-4.9%).
  • The PsA prevalence was 22.7% (20.6%-25.0%) in European, 21.5% (15.4%-28.2%) South American, 19.5% (17.1%-22.1%) North American, 15.5% (0.009%-51.5%) African, and 14.0% (11.7%-16.3%) in Asian psoriasis patients.
  • The prevalence of PsA was 23.8% (20.1%-27.6%) in studies where the CASPAR was applied.
  • The incidence of PsA among psoriasis patients ranged from 0.27 to 2.7 per 100 person-years.
Citation:

Alinaghi F, Calov M, Kristensen LE, et al. Prevalence of psoriatic arthritis in patients with psoriasis: A systematic review and meta-analysis of observational and clinical studies. [Published online ahead of print June 18, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.06.027.

This Week's Must Reads

Disease Burden of Atopic Dermatitis in the US, J Invest Dermatol; ePub 2018 Oct 30; Chiesa Fuxench, et al

Psoriasis Associated with Sexual Dysfunction, JAMA Dermatol; ePub 2018 Oct 10; Molina-Leyva, et al

Association Between Psoriasis and Suicide Examined, Dermatolog Ther; ePub 2018 Oct 12; Liang, et al

Study: More Than 85% of Surgeons Use Skin Hooks, Dermatolog Surg; ePub 2018 Oct 9; Clark, et al

FDA Approves Hyrimoz for Plaque Psoriasis, Sandoz news release; 2018 Oct 31

Must Reads in Psoriasis

Psoriasis Associated with Sexual Dysfunction, JAMA Dermatol; ePub 2018 Oct 10; Molina-Leyva, et al

Association Between Psoriasis and Suicide Examined, Dermatolog Ther; ePub 2018 Oct 12; Liang, et al

FDA Approves Hyrimoz for Plaque Psoriasis, Sandoz news release; 2018 Oct 31

Psoriasis Linked with Inflammatory Bowel Disease, JAMA Dermatol; ePub 2018 Oct 24; Fu, Lee, et al

Treatment Patterns Among Patients with Psoriasis, J Med Econ; ePub 2018 Oct 25; Murage, et al