Mohs micrographic surgery (MOHS) appears to be as effective as wide local excision (WLE) in treating early stage Merkel cell carcinoma (MCC), a recent study found. Researchers performed a retrospective review of all cases in the National Cancer Data Base (NCDB) of clinical Stage I-II MCC treated with WLE or MOHS. They found:
- 1,795 cases of Stage I-II MCC were identified who underwent WLE (n=1,685) or MOHS (n=110).
- There was no difference in residual tumor on surgical margins between the 2 treatment groups.
- On multivariate analysis, there was no difference in overall survival between the treatment modalities.
- There was no difference in overall survival between the 2 groups on propensity score matched analysis.
Singh B, Qureshi M, Truong MT, Sahni D. Demographics and outcomes of stage I-II Merkel cell carcinoma treated with Mohs micrographic surgery compared with wide local excision in the National Cancer Data Base. [Published online ahead of print February 3, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.01.041.
This Week's Must Reads
Dermatologist-Delivered Intervention Is Effective, JAMA Dermatology; ePub 2018 Aug 8; Mallett, et al
HRQOL in Patients with Cutaneous T-Cell Lymphoma, Int J Dermatol; ePub 2018 Aug 3; Holahan, Farah, et al
Disparities Seen in Access to Injectable Biologics , J Dermatolog Treat; ePub 2018 Aug 4; Feng, et al
Psoriasis Not Associated with Higher Dementia Risk, J Am Acad Dermatol; ePub 2018 Aug 6; Pezzolo, et al
Discerning Merkel Cell Carcinoma from Other Tumors, Am J Dermapathol; ePub 2018 Jul 24; Bandino, et al
Must Reads in Dermatologic Surgery
Post-Surgery Telephone Follow-up Gets High Marks, J Clin Aesthet Dermatol; ePub 2018 Jul 1; Forbes, et al
Anxiety Reduction Methods During Skin Surgery, JAMA Dermatology; ePub 2018 Jul 18; Yanes, et al
Safety of Dermatologic Surgery in an Office Setting, Dermatolog Surg; ePub 2018 Jun 27; Schmitt, et al
Mohs Surgery Effective for Atypical Fibroxanthoma, J Am Acad Dermatol; ePub 2018 Jul 5; Tolkachjov, et al
Surgical Management of Hidradenitis Suppurativa, J Surg Res; 2018 Sep; Ruan, Chen, Singhal, et al