Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Use of Antihistamines for AD Treatment Evaluated

J Am Acad Dermatol; ePub 2018 Jan 6; He, et al

Although antihistamines are widely used for the treatment of atopic dermatitis (AD), there is no high-level evidence to suggest that non-sedating antihistamines reduce itch in patients with AD, or that sedating antihistamines provide benefit in controlling AD symptoms (except perhaps sleep and AD co-morbidities, such as allergic rhinitis), a recent study found. The National Ambulatory Medical Care Survey (NAMCS) provided data on physician visits from 2003-2012. Sedating and non-sedating antihistamine use was identified at AD visits. There were 990,000 annual visits for AD. Researchers found:

  • Antihistamines were prescribed for AD in a significant proportion of visits across physician specialties (16-44%).
  • Dermatologists and pediatricians primarily used sedating antihistamines (58-70%), while the majority of family/general practitioners, internists, and other specialists prescribed non-sedating antihistamines for AD (55-100%).

He A, Feldman SR, Fleischer JR AB. An assessment of the use of antihistamines in the management of atopic dermatitis. [Published online ahead of print January 6, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2017.12.077.

This Week's Must Reads

Should Medical Coding Be Taught During Residency?, J Drugs Dermatol; 2018 Jun; Blecher, Halverstam, et al

Primary Closure Lengths in MMS Based on Cancer Type, Dermatolog Surg; ePub 2018 Jun 8; Theroux, et al

Citizen Pscientist: Important New Research Tool, Dermatol Ther (Heidelb); ePub 2018 Jun 6; Sanchez, et al

Acne Successfully Treated with Laser Combination, Dermatolog Surg; ePub 2018 Jun 5; Bakus, et al

FDA Approves Rituxan for Pemphigus Vulgaris, Genentech Web site; 2018 Jun 7

Must Reads in Atopic Dermatitis

Family Structure Linked with AD in US Children, J Am Acad Dermatol; ePub 2018 May 31; McKenzie, et al

Financial Burden of ED Visits for Atopic Dermatitis , J Am Acad Dermatol; ePub 2018 May 22; Kwa, et al

Trends in Atopic Dermatitis Management, J Drugs Dermatol; 2018 Feb; He, Feldman, et al

Use of Antihistamines for AD Treatment Evaluated, J Am Acad Dermatol; ePub 2018 Jan 6; He, et al

Atopic Dermatitis Linked with Serious Infections, Ann Allergy Asthma Immunol; 2018 Jan; Narla, et al