Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Use of Antihistamines for AD Treatment Evaluated

J Am Acad Dermatol; ePub 2018 Jan 6; He, et al

Although antihistamines are widely used for the treatment of atopic dermatitis (AD), there is no high-level evidence to suggest that non-sedating antihistamines reduce itch in patients with AD, or that sedating antihistamines provide benefit in controlling AD symptoms (except perhaps sleep and AD co-morbidities, such as allergic rhinitis), a recent study found. The National Ambulatory Medical Care Survey (NAMCS) provided data on physician visits from 2003-2012. Sedating and non-sedating antihistamine use was identified at AD visits. There were 990,000 annual visits for AD. Researchers found:

  • Antihistamines were prescribed for AD in a significant proportion of visits across physician specialties (16-44%).
  • Dermatologists and pediatricians primarily used sedating antihistamines (58-70%), while the majority of family/general practitioners, internists, and other specialists prescribed non-sedating antihistamines for AD (55-100%).
Citation:

He A, Feldman SR, Fleischer JR AB. An assessment of the use of antihistamines in the management of atopic dermatitis. [Published online ahead of print January 6, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2017.12.077.

This Week's Must Reads

Dermatomyositis, Negative ANA, and Malignancy Risk, J Am Acad Dermatol; ePub 2018 Nov 17; Hoesly, et al

Head/Neck Melanomas Have High Local Recurrence Risk, J Am Acad Dermatol; ePub 2018 Nov 17; Fix, et al

DOT Laser Offers Low Incidence of Adverse Effects, J Drugs Dermatol; 2018 Nov; Sarnoff, Gotkin, et al

Frontal Fibrosing Alopecia and Severity Factors , Dermatology (Karger); ePub 2018 Nov 22; Mervis, et al

Unsafe Neighborhoods Linked with Higher AD Risk, Ann Allergy Asthma Immunol; ePub 2018 Oct 26; McKenzie, et al

Must Reads in Atopic Dermatitis

Unsafe Neighborhoods Linked with Higher AD Risk, Ann Allergy Asthma Immunol; ePub 2018 Oct 26; McKenzie, et al

Gestational Weight Gain, AD in Offspring Linked, J Allergy Clin Immunol; ePub 2018 Nov 8; Drucker, et al

Racial/Ethnic Differences Examined in Persistent AD, J Invest Dermatol; ePub 2018 Nov 8; Kim, et al

As Temperatures Increase, So Do AD Office Visits , Int J Dermatol, ePub 2018 Nov 11; Fleischer

Disease Burden of Atopic Dermatitis in the US, J Invest Dermatol; ePub 2018 Oct 30; Chiesa Fuxench, et al