Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Trends in Atopic Dermatitis Management

J Drugs Dermatol; 2018 Feb; He, Feldman, et al

New topical atopic dermatitis (AD) treatments may provide an alternative to topical corticosteroids (TCS), better treatment outcomes for moderate-to-severe atopic dermatitis, and an alternative to systemic antihistamines whose efficacy in AD is unproven and whose general use in AD management is discouraged by the American Academy of Dermatology. This according to a recent examination of trends in AD treatment over time. Visits for AD were identified in the 2003-2012 National Ambulatory Medical Care Survey (NAMCS). Investigators identified TCS, antibiotics (Abx), antihistamines (AH), topical calcineurin inhibitors (TCI), and systemic immunosuppressants (SI) prescribed at AD visits. They found:

  • There were 990,000 annual visits for AD from 2003-2012 (3.2 visits/1000 people/year).
  • TCS were the most frequently used medication (59% of visits).
  • Topical calcineurin inhibitors (TCI) were the second most prescribed medication for AD among dermatologists (23% of visits), while antihistamines were second among all other physicians (16-44% of visits).
  • Unlike other medications, use of TCIs decreased over time.

He A, Feldman SR, Fleischer Jr AB. Trends in atopic dermatitis management: Comparison of 1990-1997 to 2003-2012. J Drugs Dermatol. 2018;17(2):135-140.

This Week's Must Reads

Sun Sensitivity Associated with Sunburn Prevalence, JAMA Dermatology; ePub 2018 Mar 14; Holman, et al

Low Nevus Count as a Marker for Aggressive Melanoma, Clin Exp Dermatol; ePub 2018 Feb 16; Tan, et al

Darker Skin and Side Effects of Chemical Peels, J Am Acad Dermatol; ePub 2018 Mar 5; Vemula, et al

Transplant Recipients and Residual sSCC Post-Biopsy, Dermatolog Surg; 2018 Mar; Ilyas, Zhang, et al

Are Antibiotics Overprescribed by Dermatologists?, Int J Dermatol; ePub 2018 Mar 9; Haynes, et al

Must Reads in Atopic Dermatitis

Trends in Atopic Dermatitis Management, J Drugs Dermatol; 2018 Feb; He, Feldman, et al

Use of Antihistamines for AD Treatment Evaluated, J Am Acad Dermatol; ePub 2018 Jan 6; He, et al

Atopic Dermatitis Linked with Serious Infections, Ann Allergy Asthma Immunol; 2018 Jan; Narla, et al

Association Between AD and SCC Discovered, Int J Dermatol; ePub 2017 Dec 15; Cho, Davis, et al

Severity of Scratching Useful Assessment in Trials, J Invest Dermatol; ePub 2017 Dec 11; Udkoff, et al