Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Trends in Atopic Dermatitis Management

J Drugs Dermatol; 2018 Feb; He, Feldman, et al

New topical atopic dermatitis (AD) treatments may provide an alternative to topical corticosteroids (TCS), better treatment outcomes for moderate-to-severe atopic dermatitis, and an alternative to systemic antihistamines whose efficacy in AD is unproven and whose general use in AD management is discouraged by the American Academy of Dermatology. This according to a recent examination of trends in AD treatment over time. Visits for AD were identified in the 2003-2012 National Ambulatory Medical Care Survey (NAMCS). Investigators identified TCS, antibiotics (Abx), antihistamines (AH), topical calcineurin inhibitors (TCI), and systemic immunosuppressants (SI) prescribed at AD visits. They found:

  • There were 990,000 annual visits for AD from 2003-2012 (3.2 visits/1000 people/year).
  • TCS were the most frequently used medication (59% of visits).
  • Topical calcineurin inhibitors (TCI) were the second most prescribed medication for AD among dermatologists (23% of visits), while antihistamines were second among all other physicians (16-44% of visits).
  • Unlike other medications, use of TCIs decreased over time.

He A, Feldman SR, Fleischer Jr AB. Trends in atopic dermatitis management: Comparison of 1990-1997 to 2003-2012. J Drugs Dermatol. 2018;17(2):135-140.

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Must Reads in Atopic Dermatitis

Unsafe Neighborhoods Linked with Higher AD Risk, Ann Allergy Asthma Immunol; ePub 2018 Oct 26; McKenzie, et al

Gestational Weight Gain, AD in Offspring Linked, J Allergy Clin Immunol; ePub 2018 Nov 8; Drucker, et al

Racial/Ethnic Differences Examined in Persistent AD, J Invest Dermatol; ePub 2018 Nov 8; Kim, et al

As Temperatures Increase, So Do AD Office Visits , Int J Dermatol, ePub 2018 Nov 11; Fleischer

Disease Burden of Atopic Dermatitis in the US, J Invest Dermatol; ePub 2018 Oct 30; Chiesa Fuxench, et al