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Association Between AD and SCC Discovered

Int J Dermatol; ePub 2017 Dec 15; Cho, Davis, et al

There is an increased risk of squamous cell carcinoma (SCC) development in the setting of atopic dermatitis (AD), according to a recent study. Researchers conducted a retrospective, case–control study of patients residing in Olmsted County, MN. Cases were selected from patients seen at Mayo Clinic who had an initial SCC diagnosis (either invasive SCC or SCC in situ) from January 1, 1996, through December 23, 2010. Age- and sex-matched controls were selected from patients seen at Mayo Clinic with no history of SCC before the case event date. 399 individuals with a documented history of SCC were identified and matched with 780 controls who did not have a history of SCC. Researchers found that after adjusting for race, smoking history, ionizing radiation exposure, corticosteroid and cyclosporine use, and non-SCC skin cancers, the odds ratio for SCC development between patients with history of AD vs patients without history of AD was 1.75.

Citation:

Cho JM, Davis DMR, Wetter DA, Bartley AC, Brewer JD. Association between atopic dermatitis and squamous cell carcinoma: A case–control study. [Published online ahead of print December 15, 2017]. Int J Dermatol. doi:10.1111/ijd.13857.

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Must Reads in Atopic Dermatitis

Disease Burden of Atopic Dermatitis in the US, J Invest Dermatol; ePub 2018 Oct 30; Chiesa Fuxench, et al

Link Between AD and Autoimmune Disorders, J Am Acad Dermatol; ePub 2018 Oct 1; Narla, et al

Pain and Itch: A Dual Burden in Atopic Dermatitis, Dermatitis; ePub 2018 Aug 31; Maarouf, et al

Sleep Impairment Common in Persons with AD, Dermatitis; ePub 2018 Aug 31; Li, Fishbein, et al

Atopic Dermatitis Puts Heavy Burden on Patients, Ann Asthma Allergy Immunol; ePub 2018 Jul 16; Silverberg, et al