The presence of stage 1 hypertension is associated with a significantly increased risk of preeclampsia when compared with high-risk normotensive women; however, this risk was significantly reduced with aspirin treatment. This according to a secondary analysis of the high-risk aspirin trial that included women with prior preeclampsia or diabetes mellitus (DM). Among the findings:
- 827 (81%) women were classified as normotensive; 193 (19%) were classified as stage 1 hypertensive.
- Among women receiving placebo, preeclampsia occurred significantly more often in women with state 1 hypertension compared with normotensive high-risk women after adjustment for maternal age and body mass index (BMI).
- Moreover, women with stage 1 hypertension had a significant risk reduction related to aspirin prophylaxis (risk ratio, 0.61) not seen in normointensive high-risk women.
Hauspurg A, Sutton EF, Catov JM, Caritis SN. Aspirin effect on adverse pregnancy outcomes associated with stage 1 hypertension in a high-risk cohort. [Published online ahead of print May 25, 2018]. Hypertension. doi:10.1161/HYPERTENSIONAHA.118.11196.
This Week's Must Reads
Long-Term LDL-C and CV Mortality Risk, Circulation; ePub 2018 Aug 16; Abdullah, et al
Breastfeeding and Risk of Stroke in Postmenopausal Women, J Am Heart Assoc; ePub 2018 Aug 22; Jacobson, et al
Psychosocial Stressors & AF in Older Women, Am J Cardiol; ePub 2018 Aug 17; Westcott, et al
Does Dietary Diversity Promote a Healthy Weight?, Circulation; ePub 2018 Aug 9; de Oliveira, et al
Dementia Progression in Men and Women with AF, Am J Cardiol; ePub 2018 Aug 3; Golive, et al
Must Reads in Hypertension
Clinic, Home, and Ambulatory BP & WMH Burden, Am Heart J; ePub 2018 Aug 11; White, et al
Hypertension in Blacks Higher Through Middle Age, J Am Heart Assoc; ePub 2018 Jul 11; Thomas, et al
Sex Differences & Tx Goals in Systemic Hypertension, Am J Cardiol; ePub 2018 Jun 22; Ochoa-Jimenez, et al
Effects of Binge Drinking on BP Levels in Young Adults, J Am Heart Assoc; ePub 2018 Jun 27; Piano, et al
2017 ACC/AHA BP Guideline Impact on Stroke Survivors, J Am Heart Assoc; ePub 2018 Jun 6; Lekoubou, et al