Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Resistance Exercise & Hypercholesterolemia in Men

Mayo Clin Proc; ePub 2018 Feb 8; Bakker, et al

When compared with no resistance exercise, <1 hour/week of resistance exercise, independent of aerobic exercise, is associated with a significantly lower risk of development of hypercholesterolemia in men, a recent study found. The study used data from the Aerobics Center Longitudinal Study and included 7,317 men aged 18 to 83 years (mean age, 46 years) without hypercholesterolemia at baseline. Researchers found:

  • During a median follow-up of 4 (2 to 7) years, hypercholesterolemia developed in 1,430 of 7,317 men (20%).
  • Those meeting the resistance exercise guidelines (≥2 days/week) had a 13% lower risk of development of hypercholesterolemia (HR, 0.87) after adjustment.
  • Additionally, <1 hour/week and 2 sessions per week of resistance exercise were associated with 32% and 31% lower risk of hypercholesterolemia (HR, 0.68 and 0.69), respectively, compared with no resistance exercise.
  • Higher levels of resistance exercise did no provide benefits.

Citation:

Bakker EA, Lee D, Sui X, et al. Association of resistance exercise with the incidence of hypercholesterolemia in men. [Published online ahead of print February 8, 2018]. Mayo Clin Proc. doi:10.1016/j.mayocp.2017.11.024.

This Week's Must Reads

Long-Term LDL-C and CV Mortality Risk, Circulation; ePub 2018 Aug 16; Abdullah, et al

Breastfeeding and Risk of Stroke in Postmenopausal Women, J Am Heart Assoc; ePub 2018 Aug 22; Jacobson, et al

Psychosocial Stressors & AF in Older Women, Am J Cardiol; ePub 2018 Aug 17; Westcott, et al

Does Dietary Diversity Promote a Healthy Weight?, Circulation; ePub 2018 Aug 9; de Oliveira, et al

Dementia Progression in Men and Women with AF, Am J Cardiol; ePub 2018 Aug 3; Golive, et al

Must Reads in Hypercholesterolemia

Racial Differences in Statin Use, JAMA Cardiol; ePub 2018 Jun 13; Nanna, et al

LLT Use in Patients with Elevated LDL-C, Circ Cardiovasc Qual Outcomes; ePub 2018 May 10; Virani, et al

Evolocumab in Differing Patient Populations , J Pharmacokinet Pharmacodyn; ePub 2018 May 7; Kuchimanchi, et al

LDL-C Targets in Elderly Statin Users After ACS, J Am Heart Assoc; ePub 2018 May 12; Alter, et al

Patient Perspectives on Statin Therapy, Clin Cardiol; ePub 2018 May 10; Brinton