Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Exercise Training Workloads in Patients with HF

Am Heart J; ePub 2018 Jul 10; Keteyian, et al

Among a diverse cohort of patients with heart failure (HF), an easily accessible measure of exercise capacity (metabolic equivalents of task [MET]) that is collected during cardiac rehabilitation (CR) is independently associated with the adjusted risk for both all-cause mortality and HF-specific hospitalization. Patients with HF who participated in an early outpatient program were included in the retrospective analysis. Exercise workloads upon entry and completion of CR were converted to METs. The primary outcome was all-cause mortality and the secondary outcome was HF hospitalization. Researchers found:

  • Among 707 patients, the median exercise training workload at the start and end of CR was 2.5 METs and 3.2 METs, respectively, for men and 2.2 METs and 2.9 METs, respectively, for women.
  • There were 242 deaths and 266 hospitalizations.
  • METs achieved at the end of CR had the strongest independent association with all-cause mortality (adjusted HR, 0.58) and HF hospitalization (adjusted HR, 0.62).
  • Each one 1 MET higher workload at the end of CR was associated with a 42% and 38% lower adjusted risk for all-cause mortality and HF hospitalization.

Citation:

Keteyian SJ, Kerrigan DJ, Lewis B, Ehrman JK, Brawner CA. Exercise training workloads in cardiac rehabilitation are associated with clinical outcomes in patients with heart failure. [Published online ahead of print July 10, 2018]. Am Heart J. doi:10.1016/j.ahj.2018.05.017.

This Week's Must Reads

Omega-3 Fatty Acids for Prevention of CVD, Cochrane Library; ePub 2018 Jul 18; Abdelhamid, et al

Elevated hs-CRP Among Patients with Prior MI, Am Heart J; ePub 2018 Jul 26; Pagidipati, et al

Catheter Ablation for Ventricular Arrhythmias, Am J Cardiol; ePub 2018 Jul 18; Ogunbayo, et al

PIs and CV Outcomes in Patients with HIV and HF, J Am Coll Cardiol; 2018 Jul; Alvi, Neilan, et al

Hypertension in Blacks Higher Through Middle Age, J Am Heart Assoc; ePub 2018 Jul 11; Thomas, et al

Must Reads in Heart Failure

PIs and CV Outcomes in Patients with HIV and HF, J Am Coll Cardiol; 2018 Jul; Alvi, Neilan, et al

Exercise Training Workloads in Patients with HF, Am Heart J; ePub 2018 Jul 10; Keteyian, et al

Renal Function & Exercise Training in HF Patients, Am J Cardiol; ePub 2018 Jun 23; Ambrosy, et al

Glucose-Lowering Medication Use in T2D and HF, Am Heart J; ePub 2018 Jun 15; Arnold, et al

Care for IHD and CHF Varies in VA Health System, JAMA Cardiol; ePub 2018 May 16; Groeneveld, et al