Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Racial Differences in Stroke in Patients with AF

Heart Rhythm; ePub 2018 Feb 19; Patel, et al

In patients with incident atrial fibrillation (AF), nearly half of the ischemic strokes occurred before the diagnosis of AF, a recent study found. Findings from the Penn Atrial Fibrillation Free study included 56,835 patients who were free of AF at the index visit. Researchers developed an inception cohort of 3,507 patients with incident AF and without any remote history of stroke. Racial differences in strokes that occurred before and after AF diagnosis were assessed. Among the findings:

  • There were 538 patients with ischemic strokes and 54 with hemorrhagic strokes.
  • Compared with whites, blacks had a higher risk of developing an ischemic stroke that persisted whether the stroke occurred in the period either before or after AF diagnosis.
  • Nearly half of the ischemic strokes occurred within a 6-month period before the diagnosis of AF.
  • 53% of the ischemic strokes occurred a median of 3.6 years after AF diagnosis.

Citation:

Patel PJ, Katz R, Borovskiy Y, et al. Race and stroke in an atrial fibrillation inception cohort: Findings from the Penn Atrial Fibrillation Free study. [Published online ahead of print February 19, 2018]. Heart Rhythm. doi:10.1016/j.hrthm.2017.11.025.

This Week's Must Reads

Relevance of Health Literacy to CV Health, Circulation; ePub 2018 Jun 4; Magnani, et al

Can Biomarkers Predict Causes of Death in AF?, Circulation; ePub 2018 Jun 5; Sharma, et al

Aspirin Benefit in Adverse Pregnancy Outcomes, Hypertension; ePub 2018 May 25; Hauspurg, et al

Care for IHD and CHF Varies in VA Health System, JAMA Cardiol; ePub 2018 May 16; Groeneveld, et al

Comparing Hypertension Guidelines in CV Events, JAMA Cardiol; ePub 2018 May 23; Bundy, et al

Must Reads in Arrhythmias & EP

Can Biomarkers Predict Causes of Death in AF?, Circulation; ePub 2018 Jun 5; Sharma, et al

DOACs vs Warfarin in Non-Valvular AF Patients, Circulation; ePub 2018 May 24; Nazha, et al

Burden of AF With Risk of Stroke in Paroxysmal AF, JAMA Cardiol; ePub 2018 May 16; Go, et al

Efficacy of NOACs in Patients with AF and VHD, J Am Heart Assoc; ePub 2018 Apr 5; Briasoulis, et al

Racial Differences in Stroke in Patients with AF, Heart Rhythm; ePub 2018 Feb 19; Patel, et al