Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Bowen’s Disease Lesions Can Mimic Those of SK

Int J Dermatol; 2017 Oct; Yang, Lin, Fang, et al

Some lesions of Bowen’s disease are often difficult to be differentiated from seborrheic keratosis, actinic keratosis, lichen planus-like keratosis, and others, according to a recent study. Therefore, it is necessary to fully describe the dermoscopic features of the disease, considering differential diagnosis. 146 lesions with a histopathological diagnosis of Bowen's disease were consecutively included in this study. All lesions were imaged with dermoscopy and analyzed for dermoscopic features. Researchers found:

  • The dermoscopic features most frequently observed in our series of lesions were scales (78.8%), glomerular vessels (69.2%), yellow crusts (56.8%), focal hemorrhage (55.5%), focal/multifocal hypopigmentation (44.5%), and linear irregular vessels (42.5%).
  • 2 new dermoscopic signs in BD were also discovered: the double-edge sign (30.1%) and the clusters of brown structureless areas (38.4%).
  • The recognition of these 2 new dermoscopic signs of BD, and fully understanding BD’s dermoscopic features, will help clinicians in differential diagnosis.

Citation:

Yang Y, Lin J, Fang S, Han S, Song Z. What's new in dermoscopy of Bowen's disease: Two new dermoscopic signs and its differential diagnosis. Int J Dermatol. 2017;56(10):1022-1025. doi:10.1111/ijd.13734.