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Bowen’s Disease Lesions Can Mimic Those of SK

Int J Dermatol; 2017 Oct; Yang, Lin, Fang, et al

Some lesions of Bowen’s disease are often difficult to be differentiated from seborrheic keratosis, actinic keratosis, lichen planus-like keratosis, and others, according to a recent study. Therefore, it is necessary to fully describe the dermoscopic features of the disease, considering differential diagnosis. 146 lesions with a histopathological diagnosis of Bowen's disease were consecutively included in this study. All lesions were imaged with dermoscopy and analyzed for dermoscopic features. Researchers found:

  • The dermoscopic features most frequently observed in our series of lesions were scales (78.8%), glomerular vessels (69.2%), yellow crusts (56.8%), focal hemorrhage (55.5%), focal/multifocal hypopigmentation (44.5%), and linear irregular vessels (42.5%).
  • 2 new dermoscopic signs in BD were also discovered: the double-edge sign (30.1%) and the clusters of brown structureless areas (38.4%).
  • The recognition of these 2 new dermoscopic signs of BD, and fully understanding BD’s dermoscopic features, will help clinicians in differential diagnosis.


Yang Y, Lin J, Fang S, Han S, Song Z. What's new in dermoscopy of Bowen's disease: Two new dermoscopic signs and its differential diagnosis. Int J Dermatol. 2017;56(10):1022-1025. doi:10.1111/ijd.13734.