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Caffeine from Coffee Inversely Linked with Rosacea

JAMA Dermatol; ePub 2018 Oct 17; Li, Chen, et al

Increased caffeine intake from coffee was inversely associated with the risk of incident rosacea, according to a recent study. This cohort study included 82,737 women in the Nurses’ Health Study II (NHS II) with follow-up conducted biennially between 1991 and 2005. All analysis took place between June 2017 and June 2018. Data on coffee, tea, soda, and chocolate consumption were collected every 4 years during follow-up. Researchers found:

  • During 1,120,051 person-years of follow-up, 4,945 incident cases of rosacea were identified.
  • After adjustment for other risk factors, an inverse association was found between increased caffeine intake and risk of rosacea (hazard ratio [HR] for the highest quintile of caffeine intake vs the lowest, 0.76).
  • A significant inverse association with risk of rosacea was also observed for caffeinated coffee consumption (HR, 0.77 for those who consumed ≥4 servings/day vs those who consumed <1/month), but not for decaffeinated coffee (HR, 0.80).
  • Further analyses found that increased caffeine intake from foods other than coffee (tea, soda, and chocolate) was not significantly associated with decreased risk of rosacea.

Li S, Chen ML, Drucker AM, et al. Association of caffeine intake and caffeinated coffee consumption with risk of incident rosacea in women. [Published online ahead of print October 17, 2018]. JAMA Dermatol. doi:10.1001/jamadermatol.2018.3301.