Prurigo nodularis (PN), a pruritic dermatosis that itches intensely and can reduce quality of life, disproportionately affects African Americans and is associated with several systemic conditions including HIV, chronic kidney disease, and diabetes, according to a recent study. Researchers conducted a cross-sectional study of patients aged ≥18 years seen at the Johns Hopkins Health System (JHHS) between December 6, 2012, and December 6, 2017. They found:
- Over the last 5 years, 909 patients with PN were seen at JHHS.
- African American patients were 3.4 times more likely to have PN than white patients.
- PN was significantly associated with a variety of systemic, cardiovascular, and psychiatric comorbidities when compared to race-matched controls, including chronic kidney disease, chronic hepatitis C, chronic obstructive pulmonary disease, congestive heart failure, depression, and atopic dermatitis.
- Black patients with PN were 10.5 times more likely to have HIV than race-matched controls with atopic dermatitis, and 8 times more likely to have HIV than African American patients with psoriasis.
Boozalis E, Tang O, Patel S, et al. Ethnic differences and comorbidities of 909 prurigo nodularis patients. [Published online ahead of print May 4, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.04.047.
This Week's Must Reads
Health Care Screening, Skin Cancer Risk Link Found, JAMA Dermatology; ePub 2018 Dec 26; Drucker, et al
Vitamin D Linked with Eczema in Non-Hispanic Whites, Allergy; ePub 2018 Dec 27; Wei, Jaleel, et al
Mohs Surgery Beneficial for Melanoma of Head/Neck, Dermatolog Surg; ePub 2018 Dec 13; Demer, et al
Study: Vitiligo and Major Depression Disorder Linked, J Am Acad Dermatol; ePub 2018 Dec 5; Vallerand, et al
Habitual Nail Biting, Psychiatric Disorders Linked , Am J Clin Dermatol; 2018 Dec; Winebrake, et al
Must Reads in Rare Diseases
Dermatomyositis, Negative ANA, and Malignancy Risk, J Am Acad Dermatol; ePub 2018 Nov 17; Hoesly, et al
Cutaneous Pleomorphic Sarcoma Prognosis Examined, J Am Acad Dermatol; ePub 2018 Nov 8; Ibanez, et al
Early Desmoplastic Melanoma Treatment Comparison, Melanoma Res; ePub 2018 Oct 31; Abbott, et al
Prevalence of Acne Vulgaris Among Patients with HS, J Am Acad Dermatol; ePub 2018 Oct 1; Wertenteil, et al
Pemphigoid Autoimmune Disorder Rare in US, J Am Acad Dermatol; ePub 2018 Aug 27; Wertenteil, et al