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Pemphigoid Autoimmune Disorder Rare in US

J Am Acad Dermatol; ePub 2018 Aug 27; Wertenteil, et al

Pemphigoid—an autoimmune disorder that causes skin rashes and blistering on the legs, arms, and abdomen—is rare in the US, according to a recent study. Patients aged ≥60 years comprise the majority of cases. Researchers conducted a cross-sectional analysis using electronic health records data for a demographically heterogeneous population-based sample of >55 million patients across all 4 census regions. They found:

  • Overall pemphigoid prevalence was 0.012%, or 12 pemphigoid patients per 100,000.
  • Prevalence of pemphigoid among those aged >60 years was 0.038%, or 37.7 per 100,000.
  • Prevalence increased approximately 2-fold within each successive age group and was highest among patients aged >90 years (123.6 per 100,000).
  • Adjusted prevalence in women was 12.7 per 100,000, slightly more than that of men (11.0 per 100,000).
  • Adjusted prevalence was similar for African Americans (15.4 per 100,000) and Caucasians (13.5 per 100,000).
Citation:

Wertenteil S, Garg A, Strunk A, Alloo A. Prevalence estimates for pemphigoid in the United States: A gender and age adjusted population analysis. [Published online ahead of print August 27, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.08.030.