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Risk of Atherosclerotic CVD Among Patients With Psoriasis

Appropriate medical screening for possible cardiovascular comorbidities is warranted in Asian patients with psoriasis according to disease severity and gender, a new study found. The nationwide population-based cohort study included >1.7 million Koreans with a 15-year follow-up period. The period prevalence of psoriasis was 0.33% among baseline participants. Among the findings:

  • In Cox proportional hazard analyses, individuals with psoriasis had a higher adjusted hazard ratio (HR) for incidence of overall atherosclerotic cardiovascular disease (CVD) (HR 1.18) compared with controls.
  • Subgroup analyses revealed that the risk for myocardial infarction was commonly increased in both sexes with moderate to severe psoriasis (male: HR 2.09; female: HR 3.23), whereas the risk of ischemic stroke was specifically increased in female individuals with moderate to severe psoriasis (HR 2.02).

Citation:

Jung KJ, et al. Increased risk of atherosclerotic cardiovascular disease among patients with psoriasis in Korea: A 15-year nationwide population-based cohort study. [Published online ahead of print August 20, 2019]. J Dermatol. doi: 10.1111/1346-8138.15052.