Researchers have developed a single-center, longitudinal psoriasis/psoriatic arthritis (PsA) registry to better define longitudinal disease characteristics, perform biomarker studies, and examine treatment trends. Psoriasis and PsA, according to researchers, are related conditions with poorly defined transition among them, risk factors for progression, complex treatment algorithms, and biomarkers for treatment response and long-term outcomes. Recognizing this, they developed the Brigham Cohort, including biorepository, which captures relevant disease markers and treatment choices in a circumscribed population with a defined catchment area. They searched electronic medical records (EMR) for patients with visits in the last year for psoriasis or PsA and formed the potentially eligible registry population. Baseline patient and provider questionnaires were developed using standardized measures, including demographics, comorbidities, medications, specific disease characteristics, functional status, quality of life, mental health, and resource use. Some key findings:
- Searching the Brigham EMR system from 2013 through 2014 revealed 1,694 patients with psoriasis and 1,028 with PsA.
- Their mean age was 55 years and 53% were female.
- Of these, 17% had diabetes, 38% hyperlipidemia, and 45% hypertension.
- The median body mass index (BMI) was 29.6.
Schneeweiss M, Merola JF, Karlson EW, Solomon DH. Rationale and design of the Brigham Cohort for psoriasis and psoriatic arthritis registry (COPPAR). [Published online ahead of print August 16, 2017]. BMC Dermatol. doi:10.1186/s12895-017-0063-8.
This Week's Must Reads
Link Found Between AD, Depression, Suicidal Ideation , J Am Acad Dermatol; 2019 Feb; Patel, et al
Patients with Persistent Post-Chemotherapy Alopecia, JAMA Dermatol; ePub 2019 Mar 6; Freites-Martinez, et al
Risk Prediction of In-Hospital Mortality for SJS/TEN, JAMA Dermatol; ePub 2019 Mar 6; Noe, et al
Melanoma Rates Before and After AJCC 7 Enactment, JAMA Dermatol; ePub 2019 Mar 6; Isom, et al
Must Reads in Psoriasis
Inflammatory Diet Not a Risk Factor for Psoriasis, J Am Acad Dermatol; ePub 2019 Feb 21; Bridgman, et al
Patient Satisfaction: Biologic vs Non-Biologic Use, J Cutan Med Surg; ePub 2019 Feb 25; Ighani, et al
Stigma-Stress Among People Living with Psoriasis, Am J Health Behav; 2019 Mar; Parkhouse
Subclinical Atherosclerosis Screening in Psoriasis, PLoS One; ePub 2019 Feb 8; Gonzalez-Cantero, et al
Association Found Between Psoriasis and Vitiligo, Am J Clin Dermatol; 2019 Feb; Yen, Chi