Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Psoriasis Linked with Periodontal Inflammation

J Invest Dermatol; ePub 2019 Jan 2; Woeste, et al

Psoriasis patients showed significantly higher values for parameters addressing periodontal inflammation, according to a recent study. Therefore, psoriasis management should include regular dental checks on periodontal status and respective treatment where required. Researchers conducted a prospective study comparing psoriasis patients with controls. 100 psoriasis patients presenting at the outpatients’ service of a specialized psoriasis center and 101 non-psoriatic controls were included in the study. Oral health was assessed using standardized measures including Bleeding on Probing (BOP), Community Periodontal Index (CPI), and dental parameters according to the DMFT-index (cumulative index; teeth registered as decayed [D], missing [M], and filled [F]). For analysis, a post-matching strategy was applied, with 53 pairs of psoriasis and non-psoriatic patients where relevant factors with possible impact on oral health status were considered. Logistic regression analyses were executed on the entire psoriasis and control population. They found:

  • The matched psoriasis group had significantly higher values of BOP and CPI compared to matched controls.
  • Logistic regression analyses identified significant correlations of the psoriasis group with high BOP and CPI values, not, however, with missing teeth.
Citation:

Woeste S, Graetz C, Gerdes S, Mrowietz U. Oral health in patients with psoriasis—A prospective study. [Published online ahead of print January 2, 2019]. J Invest Dermatol. doi:10.1016/j.jid.2018.12.014.

This Week's Must Reads

TNF inhibitor prices rose despite increased drug class competition, San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

List of medications linked to drug-induced lupus expands, Arnaud L et al. Ann Rheum Dis. 2019 Feb 4. doi: 10.1136/annrheumdis-2018-214598

HLA Antigen Mismatch Linked with Skin Cancer Risk, JAMA Dermatology; ePub 2019 Jan 23; Gao, Twigg, et al

Poor Prognosis for Thin Ulcerated Melanomas Found, J Am Acad Dermatol; ePub 2019 Jan 14; Hawkins, et al

Association Between AD and Mental Health Disorders, Dermatitis; ePub 2018 Dec 18; Hsu, Smith, et al

Must Reads in Psoriasis

TNF inhibitor prices rose despite increased drug class competition, San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

CD123 Can Help Distinguish Psoriasis from AGEP, J Cutan Pathol; ePub 2019 Jan 22; Vyas, et al

Metabolic Syndrome Linked to Psoriasis Risk, Br J Dermatol; 2019 Jan; Snekvik, et al

Causal Link Found Between BMI and Psoriasis, PLoS Med; ePub 2019 Jan 31; Budu-Aggrey, et al

Membership in Psoriasis Patient Group Beneficial, Arch Dermatol Res; 2018 Dec; Langenbruch, et al