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Psoriasis Linked with Inflammatory Bowel Disease

JAMA Dermatol; ePub 2018 Oct 24; Fu, Lee, et al

Psoriasis is significantly associated with inflammatory bowel disease (IBD), according to a recent study. Therefore, gastroenterology consultation may be indicated when patients with psoriasis present with bowel symptoms. For this systematic review and meta-analysis, literature was searched for relevant studies from inception to January 17, 2018. Case-control, cross-sectional, or cohort studies that examined either the odds or risk of IBD in patients with psoriasis were included. Researchers found:

  • A total of 5 case-control or cross-sectional studies and 4 cohort studies with 7,794,087 study participants were included.
  • Significant associations were found between psoriasis and Crohn’s disease (odds ratio, 1.70) and between psoriasis and ulcerative colitis (odds ratio, 1.75).
  • Patients with psoriasis had an increased risk of Crohn’s disease (risk ratio, 2.53) and ulcerative colitis (risk ratio, 1.71).

Fu Y, Lee C-H, Chi C-C. Association of psoriasis with inflammatory bowel disease.

A systematic review and meta-analysis. [Published online ahead of print October 24, 2018]. JAMA Dermatol. doi:10.1001/jamadermatol.2018.3631.