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Previously Diagnosed Psoriasis and Dementia Linked

In a population-based study, more patients with dementia had prior psoriasis than did patients with bullous pemphigoid (BP). Researchers explored the association between previously diagnosed psoriasis and dementia in Taiwan. They identified 7,118 individuals with a diagnosis of dementia; a further 21,354 sex- and aged-matched individuals were randomly selected as controls. Patients with BP were chosen as a control group. Among the findings:

  • Of the 28,472 individuals, 2.2%, 3.0%, and 1.5% of the total, case and control groups, respectively, had been diagnosed with psoriasis.
  • After adjustments, the odds ratio (OR) of diagnosed psoriasis for the case group was 1.46 compared with the control group.
  • No significant differences in prior BP were observed between the dementia and control groups.

Citation:

Lin CC, Lin HC, Chiu HW. Association between psoriasis and dementia: A population-based case-control study. Am J Clin Dermatol. 2019;20(3):457-463. doi: 10.1007/s40257-018-00420-8.