Key clinical point: Cutaneous psoriasis shows greater heritability than psoriatic arthritis or psoriasis vulgaris.
Major finding: Genetic variants make a greater contribution to phenotypic variation in cutaneous psoriasis.
Study details: An analysis of a genome-wide association study involving 2,938 people with psoriasis vulgaris, 1,155 with cutaneous psoriasis, 715 with psoriatic arthritis, and 3,117 unaffected controls.
Disclosures: The study was supported by the Atlantic Innovation Fund. The authors reported having no conflicts of interest.
Li Q et al. Sci Rep. 2020 Mar 18. doi: 10.1038/s41598-020-61981-5