Significant bidirectional associations were observed between psoriasis and inflammatory bowel disease (IBD) in recent study. Meta-analysis was performed to estimate the prevalence and association between IBD and psoriasis. The primary outcomes were the proportion of psoriasis patients with IBD and vice versa, as well as the association of IBD in psoriasis and psoriasis in IBD, respectively. Results were based on quantitative analysis of 93 studies. Researchers found:
- The prevalence of psoriasis in Crohn’s disease (CD) and ulcerative colitis (UC) was 3.6% and 2.8%, respectively, while the presence of CD and UC was 0.7% and 0.5%, respectively, among patients with psoriasis.
- Presence of CD or UC was significantly associated with psoriasis given by odds ratio (OR)=2.0 and OR=1.5.
- Presence of psoriasis was significantly associated with CD and UC.
Alinaghi F, et al. Global prevalence and bidirectional association between psoriasis and inflammatory bowel disease – a systematic review and meta-analysis. [Published online ahead of print August 30, 2019]. J Crohns Colitis. doi: 10.1093/ecco-jcc/jjz152.