Clinical Edge

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CAD Prevalence Higher in Patients With Psoriasis

Patients with psoriasis have a higher prevalence of subclinical coronary artery disease (CAD), a new study found. The meta-analysis included studies examining CAD prevalence and burden detected by coronary calcium score (CCS) with or without cardiac computed tomography angiography (CCTA) in patients with psoriasis without prior CAD vs controls. Researchers found:

  • 14 eligible studies provided data on 1,427 patients with psoriasis and 9,670 controls.
  • Patients with psoriasis had an increased risk of CAD and for more severe CAD the risk was increased vs controls.
  • The risk of high-risk coronary plaques identified by CCTA was also significantly higher in patients with psoriasis.


Kaiser H, et al. Coronary artery disease assessed by computed tomography in patients with psoriasis: A systematic review and meta-analysis. [Published online ahead of print September 3, 2019]. Dermatology. doi: 10.1159/000502138.