Psoriasis was significantly associated with self-reported hypercholesterolemia and hospital-diagnosed hypertension, according to a recent investigation of expectant mothers. Researchers investigated the association between psoriasis and cardiometabolic comorbidity, taking body mass index and smoking into account. The population comprised expectant mothers in a national birth cohort; 2,435 women with psoriasis (2.90%) and 81,388 women without were identified. During pregnancy, the women were asked about physician-diagnosed psoriasis. Any association with self-reported cardiometabolic comorbidity 11 years later was assessed using logistic regression. The cohort was also followed up for hospital-diagnosed comorbidity, including cardiac death, until December 31, 2014, and the risk was assessed using Cox regression. This study concluded that women with psoriasis have an increased risk of developing cardiometabolic comorbidity in early adult life.
Blegvad C, Nybo Andersen AM, Adam A, Zachariae C, Skov L. Psoriasis as a predictor of cardiometabolic comorbidity in women: A study based on the Danish National Birth Cohort. Acta Derm Venereol. 2019;99(3):274-278. doi:10.2340/00015555-3090.