Clinical Edge

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Topical Calcineurin Inhibitors Beneficial for Patients With Vitiligo

Key clinical point: Both TCI monotherapy and TCI plus phototherapy are beneficial treatments for patients with vitiligo.

Major finding: For TCI plus phototherapy, an at least mild response was achieved in 89.5% (95% CI, 81.1%-97.9%) of 433 patients in eight studies.

Study details: A systematic review and meta-analysis of 56 studies on treatment with topical calcineurin inhibitors for patients with vitiligo.

Disclosures: The authors report no conflicts of interest.


Lee JH et al. JAMA Dermatol. 2019 May 29. doi: 10.1001/jamadermatol.2019.0696.