Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Risk Factors for Skin Cancer in Non-White Persons

J Am Acad Dermatol; ePub 2019 Jan 28; Nadhan, et al

As the majority of the US population will consist of non-white individuals by the year 2043, it is essential that both physicians and patients are educated about skin cancer in non-white individuals. However, a recent investigation reports that emphasis should also be placed on active examination of sun-protected areas in non-whites and recognition of the relationship between human papilloma virus (HPV) and genital squamous cell carcinoma (SCC) lesions. Smoking cessation should also be integrated in dermatologic counseling of all patients. Researchers conducted an Institutional Review Board (IRB)-approved retrospective chart review of all non-white individuals who had received a biopsy-proven diagnosis of skin cancer from June 2008 to June 2015. They found:

  • SCC was the most commonly diagnosed skin cancer in black and Asian populations, while basal cell carcinoma (BCC) was the most common skin cancer in Hispanics.
  • Blacks exhibited the majority of their SCC lesions in sun-protected areas, particularly the anogenital area.
  • On average, current smokers were diagnosed with skin cancer 12.27 years earlier than former smokers and 9.36 years earlier than non-smokers.

Nadhan KS, Chung CL, Buchanan EM, et al. Risk factors for keratinocyte carcinoma skin cancer in nonwhite individuals: A retrospective analysis. [Published online ahead of print January 28, 2019]. J Am Acad Dermatol. doi:10.1016/j.jaad.2019.01.038.