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Nevus Development Trajectory from Age 3 to 16 Years

JAMA Dermatology; ePub 2018 Sep 12; Asdigian, et al

Youths are at risk for nevus development beginning in early childhood and continuing through mid-adolescence, according to a recent study. Therefore, exposure to ultraviolet (UV) light during this period should be reduced, particularly on body sites intermittently exposed to the sun, where nevi accumulate through mid-adolescence. This annual longitudinal observational cohort study of nevus development was conducted among 1,085 Colorado youths aged 3 to 16 years. Data analysis was conducted between February 1, 2015, and August 31, 2017. A total of 557 girls and 528 boys (150 [13.8%] Hispanic participants) born in 1998 were included. Researchers found:

  • Median total body nevus counts increased linearly among non-Hispanic white boys and girls between the ages of 3 and 16 years.
  • Median total body nevus counts were lower among Hispanic white children compared with non-Hispanic white children, but they followed a largely linear trend that varied by sex.
  • Nevus counts on body sites chronically exposed to the sun increased over time but leveled off by age 16.
  • Nevus counts on sites intermittently exposed to the sun followed a strong linear pattern through age 16.

Asdigian NL, Barón AE, Morelli JG, et al. Trajectories of nevus development from age 3 to 16 years in the Colorado Kids Sun Care Program cohort. [Published online ahead of print September 12, 2018]. JAMA Dermatology. doi:10.1001/jamadermatol.2018.3027.