Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Melanoma Surgical Method Mortality Data Analyzed

Dermatolog Surg; ePub 2017 Dec 8; Trofymenko, et al

Patients with melanoma of the face treated with Mohs micrographic surgery (MMS) had similar melanoma-specific mortality or overall survival outcome as patients treated by other surgical modalities, a recent study found. Researchers conducted a retrospective review of Surveillance, Epidemiology, and End Results registries for patients diagnosed with melanoma of the face between 2003 and 2012; the query resulted in 43,443 records. They found:

  • Patients with melanoma were more likely to undergo narrow margin incision (NME) (57.79%) than wide margin incision (WME) (27.86%) or MMS (14.36%).
  • Overall 5-year risk of death was higher with WME and NME relative to MMS after adjusting for patient demographics, residence socioeconomic factors, and tumor characteristics.
  • No statistically significant difference in melanoma-specific mortality was found between different surgical methods on multivariate analysis.
Citation:

Trofymenko O, Bordeaux JS, Zeitouni NC. Melanoma of the face and Mohs micrographic surgery: Nationwide mortality data analysis. [Published online ahead of print December 8, 2017]. Dermatolog Surg. doi:10.1097/DSS.0000000000001429.

This Week's Must Reads

Health Care Screening, Skin Cancer Risk Link Found, JAMA Dermatology; ePub 2018 Dec 26; Drucker, et al

Vitamin D Linked with Eczema in Non-Hispanic Whites, Allergy; ePub 2018 Dec 27; Wei, Jaleel, et al

Mohs Surgery Beneficial for Melanoma of Head/Neck, Dermatolog Surg; ePub 2018 Dec 13; Demer, et al

Study: Vitiligo and Major Depression Disorder Linked, J Am Acad Dermatol; ePub 2018 Dec 5; Vallerand, et al

Habitual Nail Biting, Psychiatric Disorders Linked , Am J Clin Dermatol; 2018 Dec; Winebrake, et al

Must Reads in Melanoma

Health Care Screening, Skin Cancer Risk Link Found, JAMA Dermatology; ePub 2018 Dec 26; Drucker, et al

Mohs Surgery Beneficial for Melanoma of Head/Neck, Dermatolog Surg; ePub 2018 Dec 13; Demer, et al

Factors Associated with Suspected Skin Cancers , J Am Acad Dermatol; ePub 2018 Dec 10; Beaulieu, et al

High Birth Weight, Early UV Exposure, and Melanoma, Epidemiology; ePub 2018 Nov 29; Wojcik, et al

Head/Neck Melanomas Have High Local Recurrence Risk, J Am Acad Dermatol; ePub 2018 Nov 17; Fix, et al