Clinical Edge

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Exogenous Boosting Against Shingles Not as Robust as Previously Thought

Key clinical point: Exposure to children with chickenpox reduces the incidence of shingles in adults, but does not provide complete protection.

Major finding: Chickenpox exposure from children in their households reduced the incidence of shingles in adults 33% over 2 years, and 27% out to 20 years.

Study details: Self-controlled case series with almost 10,000 adults.

Disclosures: There was no external funding, and the lead investigator had no relevant disclosures. One investigator reported research grants from GSK and Merck, both makers of chickenpox and shingles vaccines.


Forbes H et al. BMJ 2020 Jan 22;368:l6987.