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Alopecia Areata Associated with Impaired HRQoL

J Am Acad Dermatol; 2018 Sep; Liu, King, et al

Children with alopecia areata (AA) suffer poor health-related quality of life (HRQoL), and notably, so do their parents, according to a recent study. Similarly, the negative impact of AA on adults is also seen in their spouses. To further understand the impact of AA on children, adults, and their families, researchers developed an anonymous questionnaire containing several HRQoL. 292 adults, 91 children, and 229 family members took part. They found:

  • Overall, adults tried 2.9 ± 1.4 medical therapies, including medications and procedures, and children tried 2.1 ± 1.4.
  • In all, 77.1% of adults reported impairment in HRQoL.
  • In all, 78.1% of children ages 4 to 16 years with AA reported impairment in HRQoL; feelings of self-consciousness and skin symptoms were most frequently reported.
  • Patients were most commonly and severely affected by feelings of embarrassment and self-consciousness, followed by effects on social/leisure activities.
  • Families of children had worse Family Dermatology Life Quality Index scores than families of adults.


Liu LY, King BA, Craiglow BG. Alopecia areata is associated with impaired health-related quality of life: A survey of affected adults and children and their families. J Am Acad Dermatol. 2018;79(3):556-558.e1. doi:10.1016/j.jaad.2018.01.048.