Key clinical point: Dehydrated human umbilical cord allograft may be more beneficial than alginate dressing in the healing of stubborn diabetic foot ulcers (DFUs).
Major finding: At 12 weeks, more ulcers healed completely in the allograft group than in the alginate group (70% vs. 48%, respectively; P = .0089).
Study details: Prospective, multicenter, randomized controlled trial that assigned 155 patients with persistent DFUs to either treatment.
Disclosures: The lead author, William Tettelbach, MD, is now an employee of MiMedx, which provided research funding to all of the authors.
Tettelbach W et al. Int Wound J. 2019;16(1):122-30. doi: 10.1111/iwj.12976.
This Week's Must Reads
Must Reads in Wounds
Pyoderma Gangrenosum and Underlying Diseases, Am J Clin Dermatol; 2018 Aug; Kridin, Cohen, et al
Pyoderma Gangrenosum Comorbidities and Patient Age, JAMA Dermatology; ePub 2018 Feb 14; Ashchyan, et al
Zinc Oxide Gets High Marks for Wound Care, Dermatol Surg; ePub 2017 Jun 23; Thompson, et al
35-Year Evaluation of Surgical Treatment for HS, World J Surg; ePub 2017 Jun 13; Burney