A recent study reveals a low sensitivity of the scoring function of a digital dermoscopic image analyzer for detecting cutaneous melanomas. Therefore, physicians must apply keen clinical judgment when using such devices in the screening of suspicious pigmented skin lesions (PSLs). In this 15-year retrospective study, the histopathologies of 1,076 biopsied PSLs among a total of 2,500 imaged PSLs were collected. The biopsied PSLs were categorized as benign or malignant (cutaneous melanoma) based on histopathology. Analyzer scores (0-1.00) for these PSLs were obtained and grouped according to histopathology. Researchers found:
- At an optimized cutoff score of 0.50, a sensitivity of 56% and a specificity of 74% were achieved.
- The area under the receiver operating characteristics curve was 0.698, indicating poor accuracy as a diagnostic tool.
del Rosario F, Farahi JM, Drendel J, et al. Performance of a computer-aided digital dermoscopic image analyzer for melanoma detection in 1,076 pigmented skin lesion biopsies. J Am Acad Dermatol. 2018;78(5):927-934.e6. doi:10.1016/j.jaad.2017.01.049.
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Melanoma Rates Before and After AJCC 7 Enactment, JAMA Dermatol; ePub 2019 Mar 6; Isom, et al
Melanoma Risk and Moderately Dysplastic Nevi, JAMA Dermatol; ePub Oct 10; Kim, Berry, et al
Sentinel Lymph Node Positivity Markers in Melanoma, J Am Acad Dermatol; ePub 2018 Sep 18; Conic, et al
Recurrent Morphological Patterns in Melanomas, J Am Acad Dermatol; ePub Aug 27; Klebanov, et al