Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Nonsterile Gloves Safe for Skin Cancer Excisions

J Cosmet Dermatol; ePub 2019 Jan 20; Michener, et al

Nonsterile gloves (NSG) are safe to use for simple excisions of cutaneous skin cancers in an outpatient dermatology clinic setting, according to a recent study. This prospective, subject‐blinded, single‐center trial randomized 93 patients presenting for routine skin cancer excisions into 2 groups. In the first group, 53 excisions were performed with NSG and in the second group 53 excisions were performed with sterile gloves (SG). Degree of wound inflammation and wound infection at 48‐72 hours post-procedure was measured. Researchers found:

  • 106 total wounds were included.
  • 0/53 were infected in the NSG group, and 0/53 were infected in the SG at the initial screening 48‐72 hours post-excision procedure.
  • The average wound inflammation score was 0.321 for the NSG group and 0.245 for the SG group.


Michener M, Xia Y, Larrymore D, McGraw T, McCarthy S. A comparison of infection rates during skin cancer excisions using nonsterile vs sterile gloves: A prospective randomized pilot study. [Published online ahead of print January 20, 2019]. J Cosmet Dermatol. doi:10.1111/jocd.12860.