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Unsafe Neighborhoods Linked with Higher AD Risk

Ann Allergy Asthma Immunol; ePub 2018 Oct 26; McKenzie, et al

US children residing in unsafe, unsupportive, or underdeveloped neighborhoods have higher prevalence and severity of atopic dermatitis (AD), according to a recent study. Researchers analyzed data from the 2007-2008 National Survey of Children's Health, including a representative sample of 79,667 children and adolescents (aged 0-17 years) in the US. Multivariable weighted logistic regression models that adjusted for sociodemographics were constructed to determine the associations of neighborhood characteristics with AD prevalence and severity. They found:

  • AD prevalence or severity were significantly increased in children residing in neighborhoods where people reportedly definitely do not help each other out, watch out for each other's children, have people to count on, and trusted adults to help the child.
  • Children also had increased odds of AD if their caregiver felt that the child was never or sometimes safe in his/her neighborhood.
  • Severe AD was less common in children residing in a neighborhood with a bookmobile or library.


McKenzie C, Silverberg JI. Associations of unsafe, unsupportive, and underdeveloped neighborhoods with atopic dermatitis in US children. [Published online ahead of print October 26, 2018]. Ann Allergy Asthma Immunol. doi:10.1016/j.anai.2018.10.022.