Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Sleep Impairment Common in Persons with AD

Dermatitis; ePub 2018 Aug 31; Li, Fishbein, et al

Sleep disturbances (SD) and sleep-related impairment (SRI) are common in adults with atopic dermatitis (AD), particularly those with severe diseases, according to a recent study. Therefore, SD and SRI should be considered when assessing burden of AD and therapeutic decisions. Researchers conducted a prospective online questionnaire-based study of 287 adults with AD, including assessment of AD severity by Patient-Oriented Eczema Measure (POEM), self-reported global AD severity, Self-Assessed Eczema Area and Severity Index and visual analog scale-itch, POEM Information System SD and SRI individual items, and T scores. They found:

  • Adults with AD commonly endorsed all SD and SRI symptoms examined; only 58 (21.8%) reported having good or very good sleep quality in the past week.
  • However, only a minority of adults with AD endorsed a more profound impact from these individual aspects of SD and SRI in the past week or POEM Information System T scores >55.
  • In particular, SD and SRI were associated with severe or very severe AD.
  • Sleep-related impairment was also associated with comorbid hay fever and/or anxiety.
Citation:

Li J, Fishbein A, Singam V, et al. Sleep disturbance and sleep-related impairment in adults with atopic dermatitis: A cross-sectional. [Published online ahead of print August 31, 2018]. Dermatitis. doi:10.1097/DER.0000000000000401.

This Week's Must Reads

Link Found Between AD, Depression, Suicidal Ideation , J Am Acad Dermatol; 2019 Feb; Patel, et al

Patients with Persistent Post-Chemotherapy Alopecia, JAMA Dermatol; ePub 2019 Mar 6; Freites-Martinez, et al

Risk Prediction of In-Hospital Mortality for SJS/TEN, JAMA Dermatol; ePub 2019 Mar 6; Noe, et al

Melanoma Rates Before and After AJCC 7 Enactment, JAMA Dermatol; ePub 2019 Mar 6; Isom, et al

Lymph Node Ratio and Survival Post-MCC Surgery, JAMA Dermatol; ePub 2019 Mar 2; Cheraghlou, et al

Must Reads in Atopic Dermatitis

Link Found Between AD, Depression, Suicidal Ideation , J Am Acad Dermatol; 2019 Feb; Patel, et al

Association Between AD and Mental Health Disorders, Dermatitis; ePub 2018 Dec 18; Hsu, Smith, et al

Adult Atopic Dermatitis Profile Varies with Age, J Allergy Clin Immunol; ePub 2019 Jan 24; Zhou, et al

Association Found Between AD and Suicidality, JAMA Dermatology; ePub 2018 Dec 12; Sandhu, et al