Patient-reported atopic dermatitis (AD) severity appears to be sufficiently valid for assessing AD severity in the clinical and epidemiological setting, according to a recent study. Researchers performed a prospective dermatology practice-based study using questionnaires and evaluation by a dermatologist (n=265). They found:
- At baseline and follow-up, patient-reported global AD severity significantly correlated with objective Scoring Atopic Dermatitis (oSCORAD, Spearman rho=0.56 and 0.49), SCORAD (0.64 and 0.56), Eczema Area Severity Index (EASI, 0.56 and 0.50), Body Surface Area (BSA, 0.52 and 0.45), Itch Numeric Rating Scale (NRS-itch, 0.60 and 0.53), Patient Oriented Eczema Measure (POEM, 0.50 and 0.48), and Dermatology Life Quality Index (DLQI, 0.50 and 0.49).
- Patient-reported moderate and severe AD vs mild AD were associated with significantly higher oSCORAD, SCORAD, EASI, BSA, NRS-itch, POEM, and DLQI.
- There was moderate concordance between patient-reported AD severity (mild, moderate, and severe) and previously developed severity strata for oSCORAD (kappa=0.39), SCORAD (kappa=0.47), EASI (kappa=0.37), NRS-itch (kappa=0.49), POEM (kappa=0.37), and DLQI (kappa=0.40).
Vakharia PP, Chopra R, Sacotte, et al. Validation of patient-reported global severity of atopic dermatitis in adults. [Published online ahead of print September 14, 2017]. Allergy. doi:10.1111/all.13309.
This Week's Must Reads
Health Care Screening, Skin Cancer Risk Link Found, JAMA Dermatology; ePub 2018 Dec 26; Drucker, et al
Vitamin D Linked with Eczema in Non-Hispanic Whites, Allergy; ePub 2018 Dec 27; Wei, Jaleel, et al
Mohs Surgery Beneficial for Melanoma of Head/Neck, Dermatolog Surg; ePub 2018 Dec 13; Demer, et al
Study: Vitiligo and Major Depression Disorder Linked, J Am Acad Dermatol; ePub 2018 Dec 5; Vallerand, et al
Habitual Nail Biting, Psychiatric Disorders Linked , Am J Clin Dermatol; 2018 Dec; Winebrake, et al
Must Reads in Atopic Dermatitis
Association Found Between AD and Suicidality, JAMA Dermatology; ePub 2018 Dec 12; Sandhu, et al
Anchoring Not Significant in Treatment of AD, J Dermatolog Treat; ePub 2018 Dec 3; Curry, et al
Unsafe Neighborhoods Linked with Higher AD Risk, Ann Allergy Asthma Immunol; ePub 2018 Oct 26; McKenzie, et al
Gestational Weight Gain, AD in Offspring Linked, J Allergy Clin Immunol; ePub 2018 Nov 8; Drucker, et al
Racial/Ethnic Differences Examined in Persistent AD, J Invest Dermatol; ePub 2018 Nov 8; Kim, et al