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Link Found Between AD, Depression, Suicidal Ideation

J Am Acad Dermatol; 2019 Feb; Patel, et al

Patients with atopic dermatitis (AD) have higher odds of depression and suicidality, according to a recent investigation. A systematic review of all published observational studies in databases that analyzed depression in AD was performed. 2 reviewers performed study title and/or abstract review and data abstraction. Pooled meta-analysis was performed by using random-effects weighting. They found:

  • Overall, 106 studies met the inclusion criteria; 36 had sufficient data for meta-analysis.
  • The prevalence of any depression was higher in persons with vs without AD (20.1% vs 14.8%).
  • Similar results were found in sensitivity analyses of studies assessing clinical depression, depressive symptoms, and adults; studies with healthy controls; and studies of low and high study quality.
  • AD was associated with significantly higher depression scale scores, parental depression, antidepressant use, and suicidality.

Citation:

Patel KR, Immaneni S, Singam V, Rastogi S, Silverberg JI. Association between atopic dermatitis, depression, and suicidal ideation: A systematic review and meta-analysis. J Am Acad Dermatol. 2019;80(2):402–410. doi:10.1016/j.jaad.2018.08.063.

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Must Reads in Atopic Dermatitis

Link Found Between AD, Depression, Suicidal Ideation , J Am Acad Dermatol; 2019 Feb; Patel, et al

Association Between AD and Mental Health Disorders, Dermatitis; ePub 2018 Dec 18; Hsu, Smith, et al

Adult Atopic Dermatitis Profile Varies with Age, J Allergy Clin Immunol; ePub 2019 Jan 24; Zhou, et al

Association Found Between AD and Suicidality, JAMA Dermatology; ePub 2018 Dec 12; Sandhu, et al