Clinical Edge

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Early onset of atopic dermatitis linked to poorer control

Key clinical point: Earlier onset of atopic dermatitis in childhood is linked to poorer control and greater chance of persistence.

Major finding: Later-onset atopic dermatitis is associated with 49% lower odds of poorer control than early onset, while children who had mid-onset disease had 29% lower odds of poorer control.

Study details: Observational cohort study in 8,015 individuals with childhood-onset atopic dermatitis; 72% had early-onset atopic dermatitis (0-2 years), 19% had mid-onset disease (3-7 years), and 9% had late-onset disease (8-17 years).

Disclosures: The study was partly supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases and the Dermatology Foundation. Three authors declared funding, consultancies, or advisory board positions with the pharmaceutical sector. No other conflicts of interest were declared.