Key clinical point: Dupilumab significantly improved symptoms of atopic dermatitis in grade school–aged children, according to new clinical trial results.
Major finding: In a cohort of children with severe AD, 33% achieved clear or nearly clear skin after 16 weeks of treatment with every 4-week dosing of the injectable medication, while 30% also achieved that mark when receiving a weight-based dose every 2 weeks, significantly better than those receiving placebo (P less than .0001 for both therapy arms) versus placebo).
Study details: Randomized, double-blind, placebo-controlled trial of 367 children aged 6-11 years of age with severe AD.
Disclosures: The study was funded by Regeneron and Sanofi. Dr. Paller reported receiving support from these two pharmaceutical companies, as well as from many others.
FROM REVOLUTIONIZING AD 2020