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Disease Burden in Adult Patients with AD

Adults with moderate-to-severe atopic dermatitis (AD) are suffering more than what would be deemed acceptable, according to a study that examined the burden of disease and individual suffering in adults with AD. The large European study included 1,189 adult patients (aged 18-87 years, 56% female) with moderate-to-severe AD. A computer assisted telephone interview was conducted to assess severity and measure quality of life in these patients. Among the findings:

  • Despite current treatment, 45% of participants still had actual moderate-to-very severe AD in patient oriented eczema measure (POEM).
  • 57% missed ≥1 day of work in the preceding year due to their skin disease.
  • Dermatology life quality index (DLQI) showed moderate to extremely large impairment in 55% of participants.
  • 10% had signs of depressive symptoms.
  • Of those suffering from severe AD, 88% stated that their AD at least partly compromised their ability to face life.


Ring J, Zink A, Arents BWM, et al. Atopic eczema: Burden of disease and individual suffering – Results from a large EU-study in adults. [Published online ahead of print April 19, 2019]. J Eur Acad Dermatol Venereol. doi:10.1111/jdv.15634.