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Anxiety and Depression in Atopic Dermatitis

In a large cohort of US adults, atopic dermatitis (AD) was associated with significantly increased anxiety and depression, a new study found. The cross-sectional, population-based study included 2,893 US adults. AD was determined using modified UK Diagnostic Criteria. Among the findings:

  • US adults with AD vs those without AD had higher prevalence of self-reported healthcare-diagnosed anxiety or depression in the past year.
  • Higher rates were primarily driven by AD severity.
  • Hospital Anxiety and Depression Scale anxiety (HADS-A) scores were consistently higher than Hospital Anxiety and Depression Scale anxiety and depression (HADSD) scores across all analyses in respondents with AD. These associations remained significant after extensively controlling for sociodemographics.
  • Anxiety and depression often go undiagnosed in adults with AD.


Silverberg JL, Gelfand JM, Margolis DJ, et al. Symptoms and diagnosis of anxiety and depression in atopic dermatitis in U.S. adults. [Published online ahead of print March 5, 2019]. Br J Dermatol. doi:10.1111/bjd.17683.