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Telangiectases Location and Distribution in Youth

J Am Acad Dermatol; ePub 2019 Feb 25; Gonzalez, et al

In a pediatric population, telangiectases at sites not included as “characteristic” by the Curaçao diagnostic criteria were common, a recent study found. Therefore, the Curaçao criteria, in regard to both number and location of telangiectases, may be inadequate in the pediatric hereditary hemorrhagic telangiectasia (HHT) population. A retrospective chart review using a standardized data collection form for site and number of telangiectases was performed for pediatric patients with HHT (age, 0-18 years) from 2005 to 2016. Researchers found:

  • Of 90 pediatric patients with HHT, 71% had ≥1 telangiectases.
  • Of all the telangiectases counted (n=319), cutaneous telangiectases were more common (73%) than oral telangiectases (27%).
  • The hands were the most frequent site, accounting for 33% of all telangiectases.
  • Adolescents were more likely than children to have cutaneous telangiectases (85% vs 50%).
  • The most frequent sites in children aged <10 years were the hands excluding the fingers (27%), fingers (25%), and face (23%).
  • Only 23% of subjects (21 of 90) presented with multiple (≥3) telangiectases at locations considered characteristic for the current consensus diagnosis guidelines (lips, oral cavity, and fingers).

Citation:

Gonzalez CD, Cipriano SD, Topham CA, et al. Localization and age distribution of telangiectases in children and adolescents with hereditary hemorrhagic telangiectasia: A retrospective cohort study. [Published online ahead of print February 25, 2019]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.11.014.