In a pediatric population, telangiectases at sites not included as “characteristic” by the Curaçao diagnostic criteria were common, a recent study found. Therefore, the Curaçao criteria, in regard to both number and location of telangiectases, may be inadequate in the pediatric hereditary hemorrhagic telangiectasia (HHT) population. A retrospective chart review using a standardized data collection form for site and number of telangiectases was performed for pediatric patients with HHT (age, 0-18 years) from 2005 to 2016. Researchers found:
- Of 90 pediatric patients with HHT, 71% had ≥1 telangiectases.
- Of all the telangiectases counted (n=319), cutaneous telangiectases were more common (73%) than oral telangiectases (27%).
- The hands were the most frequent site, accounting for 33% of all telangiectases.
- Adolescents were more likely than children to have cutaneous telangiectases (85% vs 50%).
- The most frequent sites in children aged <10 years were the hands excluding the fingers (27%), fingers (25%), and face (23%).
- Only 23% of subjects (21 of 90) presented with multiple (≥3) telangiectases at locations considered characteristic for the current consensus diagnosis guidelines (lips, oral cavity, and fingers).
Gonzalez CD, Cipriano SD, Topham CA, et al. Localization and age distribution of telangiectases in children and adolescents with hereditary hemorrhagic telangiectasia: A retrospective cohort study. [Published online ahead of print February 25, 2019]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.11.014.
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