Clinical Edge

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CVD risk in black SLE patients 18 times higher than in whites

Key clinical point: Black race is the single greatest predictor of cardiovascular disease events in systemic lupus erythematosus.

Major finding: Black race predicted an overall 500% higher risk of a cardiovascular disease event over 16 years (adjusted hazard ratio, 6.4; 95% confidence interval, 2.4-17.5; P = .0003), with a markedly increased risk during the initial 10 years, starting 2 years before diagnosis (aHR, 18; 95% CI, 2.2-141; P less than .0001).

Study details: A review of 336 patients in the Georgia Lupus Registry

Disclosures: There was no external funding, and the investigators reported no disclosures.


Garg S et al. Arthritis Rheumatol. 2019;71(suppl 10), Abstract 805.