Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Prevalence of Acne Vulgaris Among Patients with HS

J Am Acad Dermatol; ePub 2018 Oct 1; Wertenteil, et al

Patients with hidradenitis suppurativa (HS) may benefit from assessment of acne status and optimization of co-management strategies, a recent study found. Researchers conducted a cross-sectional analysis identifying adults with acne vulgaris (AV) among HS and non-HS patients using electronic health records data from a population-based sample of >55 million patients. They found:

  • Prevalence of AV among adults with HS was 15.2% (7,315 /48,050), compared to 2.9% (497,360 /16,899,470) for adults without HS.
  • Prevalence was greatest among HS patients who were female (5,870/35,790; 16.4%), aged 18-44 years (5,260/28,870; 18.2%), non-white (3,120/17,825; 17.5%), obese (5,430/35,135; 15.5%), and had polycystic ovary syndrome (PCOS) (685/2,385; 28.7%).
  • HS patients had 4.51 times the odds of having AV compared to non-HS patients, and the higher likelihood of having AV persisted across all HS subgroups.
  • The association between HS and AV was generally stronger for patients who were male, aged ≥65 years, non-whites, and obese.


Wertenteil S, Strunk A, Garg A. Overall and subgroup prevalence of acne vulgaris among patients with hidradenitis suppurativa. [Published online ahead of print October 1, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2018.09.040.

This Week's Must Reads

HLA Antigen Mismatch Linked with Skin Cancer Risk, JAMA Dermatology; ePub 2019 Jan 23; Gao, Twigg, et al

Poor Prognosis for Thin Ulcerated Melanomas Found, J Am Acad Dermatol; ePub 2019 Jan 14; Hawkins, et al

Association Between AD and Mental Health Disorders, Dermatitis; ePub 2018 Dec 18; Hsu, Smith, et al

Nonsterile Gloves Safe for Skin Cancer Excisions, J Cosmet Dermatol; ePub 2019 Jan 20; Michener, et al

Adult Atopic Dermatitis Profile Varies with Age, J Allergy Clin Immunol; ePub 2019 Jan 24; Zhou, et al

Must Reads in Acne

FDA Approves Seysara for Severe Acne Vulgaris, Paratek Pharmaceuticals, Inc. news release; 2018 Oct 2

Prevalence of Acne Vulgaris Among Patients with HS, J Am Acad Dermatol; ePub 2018 Oct 1; Wertenteil, et al

Acne Successfully Treated with Laser Combination, Dermatolog Surg; ePub 2018 Jun 5; Bakus, et al

Large Acne Study of Twins Supports Genetic Link, J Drugs Dermatol; 2018 Apr 1; Suggs, Loesch, et al

Hormonal Antiandrogen Acne Treatment Examined, Am J Clin Dermatol; ePub 2018 Mar 20; Park, et al