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Mental Health Burden of Acne Vulgaris and Rosacea

Clin Exp Dermatol; ePub 2019 Jan 31; Singam, et al

Inpatients with acne or rosacea had increased odds of comorbid mental health (MH) disorders, according to a recent study. In particular, there was an increased number of hospital admissions secondary to a primary MH disorder with coexistent acne/rosacea. Furthermore, MH comorbidities were associated with considerable excess costs among inpatients with acne or rosacea. Data were examined from the 2002–2012 US National Inpatient Sample, comprising a sample of ~20% of all US pediatric and adult hospitalizations (n=87,053,155 admissions). Researchers found:

  • A diagnosis of ≥1 MH disorder was much more common among all inpatients with vs those without a diagnosis of acne (43.7% vs 20.0%, respectively) and rosacea (35.1% vs 20.0%, respectively).
  • In multivariable logistic regression models controlling for sex, age, race/ethnicity, and insurance status, acne (adjusted OR=13.02) and rosacea (adjusted OR=1.70) were associated with significantly higher odds of a primary admission for an MH disorder (13 and 8, respectively, of 15 MH disorders examined).
  • Both acne and rosacea were associated with higher risk of mood, anxiety, impulse control, and personality disorders, and with >$2 million of excess mean annual costs of hospitalization for MH disorders in the US.

Singam V, Rastogi S, Patel KR, Lee HH, Silverberg JI. The mental health burden in acne vulgaris and rosacea: An analysis of the US National Inpatient Sample. [Published online ahead of print January 31, 2019]. Clin Exp Dermatol. doi:10.1111/ced.13919.