A recent acne study that surveyed identical and fraternal twins supports existing data that there may be a genetic phenotypic link, though social and environmental factors may also have an influence in the disease process. A survey was administered to 139 identical and fraternal twin multiples (279 subjects) at the Annual Twins Day Festival in Twinsburg, OH, on August 6-7, 2016; 1 set of triplets was included. Acne incidence, severity, and triggers were analyzed using the N-1 Chi-squared test and paired, 2-tailed t test. Researchers found:
- The proportion of concordant pairs was significantly higher in identical (64%) vs fraternal (49%) twins.
- Acne was found to be associated with polycystic ovarian syndrome (PCOS), anxiety, and asthma.
- Identical twin pairs with acne had a higher BMI and exercised significantly less than those without acne.
- Analyzing concordant twin pairs, the twin with more severe acne was more likely to report aggravation of acne with cosmetic product use and sugar intake.
Suggs A, Loesch M, Ezaldein H, Christensen L, Dawes D, Baron E. An acne survey from the world’s largest annual gathering of twins. J Drugs Dermatol. 2018;17(4):380-382.
This Week's Must Reads
Psoriasis Linked with Increased All-Cause Mortality, J Am Acad Dermatol; ePub 2018 Dec 24; Dhana, et al
Examining Patient Resistance to Psoriasis Treatment, Exp Opin Pharmacother; ePub 2018 Dec 27; Heath, et al
Psoriasis Linked with Periodontal Inflammation, J Invest Dermatol; ePub 2019 Jan 2; Woeste, et al
Psoriasis Independently Linked with Depression Risk, Br J Dermatol; 2019 Jan; Egeberg, Thyssen, Wu, et al
Health Literacy May Benefit Patients with Psoriasis, Br J Dermatol; ePub 2018 Dec 31; Larsen, et al
Must Reads in Acne
FDA Approves Seysara for Severe Acne Vulgaris, Paratek Pharmaceuticals, Inc. news release; 2018 Oct 2
Prevalence of Acne Vulgaris Among Patients with HS, J Am Acad Dermatol; ePub 2018 Oct 1; Wertenteil, et al
Acne Successfully Treated with Laser Combination, Dermatolog Surg; ePub 2018 Jun 5; Bakus, et al
Large Acne Study of Twins Supports Genetic Link, J Drugs Dermatol; 2018 Apr 1; Suggs, Loesch, et al
Hormonal Antiandrogen Acne Treatment Examined, Am J Clin Dermatol; ePub 2018 Mar 20; Park, et al