Pediatric Pearls—From Langerhans to Kawasaki : Consider Langerhans cell histiocytosis in children with refractory atopic or seborrheic dermatitis.

The cutaneous finding of perineal accentuation or desquamation should increase concerns about the possibility of Kawasaki disease. In contrast, there is much less worry about Kawasaki disease in a child with blisters or purpura.

Dr. Mancini had no conflicts of interest to disclose.

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Perineal accentuation or desquamation should increase concerns about the possibility of Kawasaki disease. DR. MANCINI