Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Rare Cutaneous Benign Tumor (RASD) Can Mimic SK

Dermatol Pract Concept; 2017 Jul; Ribiero, Leocadia, et al

Reticulated acanthoma with sebaceous differentiation (RASD) is a rare, benign cutaneous tumor with peculiar histopathologic characteristics, according to a recent review. RASD had been described under various synonyms such as superficial epithelioma with sebaceous differentiation, sebocrine adenoma, poroma with sebaceous differentiation, and seborrheic keratosis with sebaceous differentiation. Clinical differential diagnosis of RASD includes cutaneous superficial epithelial neoplasia such as Bowen’s disease, superficial basal cell carcinoma, and intraepidermal eccrine poroma.


Ribiero F, Leocadia E, Macarenco RS, et al. Reticulated acanthoma with sebaceous differentiation mimicking melanoma. Dermatol Pract Concept. 2017;7(3):35-37. doi:10.5826%2Fdpc.0703a07.

This Week's Must Reads

Predicting Disease Activity and Improvement in CLE, J Am Acad Dermatol; ePub 2018 Jul 2; Ker, Teske, et al

Prediction Tool Effective for Assessing cSCC Risk, J Invest Dermatol; ePub 2018 Jul 2; Wang, et al

Safety of Dermatologic Surgery in an Office Setting, Dermatolog Surg; ePub 2018 Jun 27; Schmitt, et al

Mohs Surgery Effective for Atypical Fibroxanthoma, J Am Acad Dermatol; ePub 2018 Jul 5; Tolkachjov, et al

FDA Approves Qbrexza for Excessive Armpit Sweating, Dermira Inc. news release; 2018 Jun 29

Must Reads in Seborrheic Keratosis

Discriminating Between Irritated SK and SCC in Situ, J Cutan Pathol; ePub 2018 May 3; Richey, Deng, et al

SKs Found Among Collision Skin Lesions, Dermatol Pract Concept; 2017 Jul; Blum, et al

FDA Approves Eskata for Seborrheic Keratosis, Aclaris news release; 2017 Dec 15

Deep Neural Networks Can Aid Skin Diagnoses, Nature; 2017 Feb 2; Esteva, Kuprel, Novoa, et al

Distinguishing Lentigo Maligna from SL/SK, J Am Acad Dermatol; 2017 Feb; Annessi, et al