Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Psoriasis and Diabetes Risk Examined in Cohort

J Am Acad Dermatol; ePub 2017 Nov 8; Wan, et al

Clinicians may measure body surface area (BSA) affected by psoriasis in order to target diabetes prevention efforts for patients with psoriasis, a recent study found. Researchers conducted a prospective, population-based, cohort study of 8,124 adults with psoriasis and 76,599 adults without psoriasis for approximately 4 years. They found:

  • 280 (3.44%) incident cases of diabetes in the psoriasis group and 1,867 (2.44%) incident cases of diabetes in those without psoriasis.
  • After adjusting for age, sex, and body mass index, the hazard ratios for developing incident diabetes were 1.21 (1.01-1.44), 1.01 (0.81-1.26), and 1.64 (1.23-2.18) in the ≤2BSA, 3-10%BSA, and >10%BSA groups compared to those without psoriasis, respectively.
  • Worldwide, an estimation included an additional 125,650 new diagnoses of type 2 diabetes mellitus per year in patients with psoriasis, as compared to those without.


Wan MT, Shin DB, Hubbard RA, Noe MH, Mehta NN, Gelfand JM. Psoriasis and the risk of diabetes: A prospective population-based cohort study. [Published online ahead of print November 8, 2017]. J Am Acad Dermatol. doi:10.1016/j.jaad.2017.10.050.

This Week's Must Reads

Sun Sensitivity Associated with Sunburn Prevalence, JAMA Dermatology; ePub 2018 Mar 14; Holman, et al

Low Nevus Count as a Marker for Aggressive Melanoma, Clin Exp Dermatol; ePub 2018 Feb 16; Tan, et al

Darker Skin and Side Effects of Chemical Peels, J Am Acad Dermatol; ePub 2018 Mar 5; Vemula, et al

Transplant Recipients and Residual sSCC Post-Biopsy, Dermatolog Surg; 2018 Mar; Ilyas, Zhang, et al

Are Antibiotics Overprescribed by Dermatologists?, Int J Dermatol; ePub 2018 Mar 9; Haynes, et al

Must Reads in Psoriasis

Treatment Preferences of Patients with Psoriasis , Arch Dermatolog Treat; ePub 2018 Feb 13; Florek, et al

TB Risk in Psoriasis Patients Using TNF Inhibitors , J Dermatolog Treat; ePub 2018 Feb 19; Lee, et al

FDA Approves Label Update for Cosentyx, Novartis news release; 2018 Feb 8

Childhood Psoriasis, Obesity, and Comorbidities, JAMA Dermatology; ePub 2018 Jan 10; Tollefson, et al

FDA Approves New Pfizer Biosimilar Ixifi, Pfizer news release; 2017 Dec 13