Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Polycystic Ovary Syndrome Linked with HS

J Invest Dermatol; ePub 2018 Feb 4; Garg, et al

Polycystic ovary syndrome (PCOS) is associated with hidradenitis suppurativa (HS), according to a recent study, and it is recommended that HS patients with symptoms or signs of androgen excess should be screened for PCOS. Researchers sought to determine prevalence of PCOS among HS patients and the strength of the association. They performed a cross-sectional analysis involving 22,990 HS patients using clinical data from a multi-health system analytics platform comprising >50 million unique patients across all census regions of the US. They found:

  • Prevalence of PCOS among patients with HS was 9.0%, compared to 2.9% in patients without HS.
  • Likelihood of HS patients having PCOS was 2.14 times that of non-HS patients, and PCOS was associated with HS across all subgroups.
  • Strength of the HS association with PCOS was similar to that of diabetes mellitus and obesity with PCOS.
  • Influence of disease severity on strength of association with PCOS could not be assessed, nor could an HS phenotype for patients also having PCOS.
Citation:

Garg A, Neuren E, Strunk A. Hidradenitis suppurativa is associated with polycystic ovary syndrome: A population-based analysis in the United States. [Published online ahead of print February 4, 2018]. J Invest Dermatol. doi:10.1016/j.jid.2018.01.009.

This Week's Must Reads

Skin Disease Prevalent Among Hospitalized Patients, J Am Acad Dermatol; ePub 2018 Dec 13; Arnold, et al

Trends in Medicare Usage by Dermatologists, JAMA Dermatology; ePub 2018 Dec 19; Ya, et al

Factors Associated with Suspected Skin Cancers , J Am Acad Dermatol; ePub 2018 Dec 10; Beaulieu, et al

Distinguishing Features of LPLK vs Lichen Planus, Int J Dermatol; ePub 2018 Dec 18; Vincek

Association Found Between AD and Suicidality, JAMA Dermatology; ePub 2018 Dec 12; Sandhu, et al

Must Reads in Mixed Topics

Skin Disease Prevalent Among Hospitalized Patients, J Am Acad Dermatol; ePub 2018 Dec 13; Arnold, et al

Distinguishing Features of LPLK vs Lichen Planus, Int J Dermatol; ePub 2018 Dec 18; Vincek

Cutaneous Lymphomas Examined in Black Patients, J Drugs Dermatol; 2018 Dec; Geller, Pulitzer, et al

Association Between Vitiligo, Depression Found , J Am Acad Dermatol; ePub 2018 Dec 5; Vallerand, et al

Association Between Psoriasis and Suicide Examined, Dermatolog Ther; ePub 2018 Oct 12; Liang, et al