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Polycystic Ovary Syndrome Linked with HS

J Invest Dermatol; ePub 2018 Feb 4; Garg, et al

Polycystic ovary syndrome (PCOS) is associated with hidradenitis suppurativa (HS), according to a recent study, and it is recommended that HS patients with symptoms or signs of androgen excess should be screened for PCOS. Researchers sought to determine prevalence of PCOS among HS patients and the strength of the association. They performed a cross-sectional analysis involving 22,990 HS patients using clinical data from a multi-health system analytics platform comprising >50 million unique patients across all census regions of the US. They found:

  • Prevalence of PCOS among patients with HS was 9.0%, compared to 2.9% in patients without HS.
  • Likelihood of HS patients having PCOS was 2.14 times that of non-HS patients, and PCOS was associated with HS across all subgroups.
  • Strength of the HS association with PCOS was similar to that of diabetes mellitus and obesity with PCOS.
  • Influence of disease severity on strength of association with PCOS could not be assessed, nor could an HS phenotype for patients also having PCOS.

Garg A, Neuren E, Strunk A. Hidradenitis suppurativa is associated with polycystic ovary syndrome: A population-based analysis in the United States. [Published online ahead of print February 4, 2018]. J Invest Dermatol. doi:10.1016/j.jid.2018.01.009.

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