Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Traumatic Exposures & Health Issues in Older Women

JAMA Intern Med; ePub 2018 Nov 19; Gibson, et al

Among midlife and older women, lifetime history of intimate partner violence (IPV) or sexual assault and symptoms of posttraumatic stress disorder (PTSD) are common and may be associated with the development and experience of menopause symptoms. This according to a cross-sectional analysis of data from a multiethnic cohort of 2,016 women aged 40 to 80 years. The primary outcomes were difficulty sleeping, vasomotor symptoms, and vaginal symptoms, assessed with standardized questionnaires. Researchers found:

  • IPV, sexual assault, and symptoms of PTSD were common in the cohort.
  • Symptoms of PTSD were associated with difficult sleeping, vasomotor symptoms, night sweats, and vaginal symptoms.
  • Emotional IPV was associated with difficult sleeping, night sweats, and pain with intercourse.
  • Physical IPV was associated with night sweats.
  • Sexual assault was associated with vaginal symptoms.

Citation:

Gibson CJ, Huang AJ, McCaw B, Subak LL, Thom DH, Van Den Eeden SK. Associations of intimate partner violence, sexual assault, and posttraumatic stress disorder with menopause symptoms among midlife and older women. [Published online ahead of print November 19, 2018]. JAMA Intern Med. doi:10.1001/jamainternmed.2018.5233.

This Week's Must Reads

TNF inhibitor prices rose despite increased drug class competition, San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

List of medications linked to drug-induced lupus expands, Arnaud L et al. Ann Rheum Dis. 2019 Feb 4. doi: 10.1136/annrheumdis-2018-214598

ACIP Updates Adult Immunization Schedule, Ann Intern Med; 2019 Feb 5; Kim, Hunter, et al

Are Automated Office BP Readings More Accurate?, JAMA Intern Med; ePub 2019 Feb 4; Roerecke, et al

Prevention of Prescription Opioid Misuse in the US, JAMA Netw Open; 2019 Feb 1; Chen, et al

Must Reads in Women's Health

Hypertensive Diseases of Pregnancy & Risk of HF, Mayo Clin Proc; ePub 2018 Dec 19; Nizamuddin, et al

Recent Childbirth a Risk Factor for Breast Cancer, Ann Intern Med; ePub 2018 Dec 11; Nichols, et al

BMI & Risk of Postpregnancy T2D in Women with HDP , Diabetes Care; ePub 2018 Nov 19; Timpka, et al

Traumatic Exposures & Health Issues in Older Women, JAMA Intern Med; ePub 2018 Nov 19; Gibson, et al

Paternal Age and Perinatal Outcomes in the US, BMJ; ePub 2018 Oct 31; Khandwala, et al