Among individuals with chronic low back pain, sleep disturbance was related significantly with chronic pain intensity and function via both direct and indirect pathways. This according to a study that included 87 individuals (64% female) with chronic low back pain but not using opioids daily who completed questionnaires assessing their sleep disturbance, chronic pain intensity, function, depression, anxiety, positive affect, and catastrophizing. Researchers found:
- Greater sleep disturbance was associated with greater pain intensity, worse function, greater emotional distress, lower positive affect, and higher levels of catastrophizing.
- In cross-sectional mediation analyses, the positive associations between sleep disturbance and chronic pain intensity were conveyed statistically not only via significant indirect effects of elevated emotional distress, lower positive affect, and greater catastrophizing associated with sleep disturbance, but also by significant direct effects of sleep disturbance on chronic pain intensity.
- The associations between sleep disturbance and impaired function were similar.
Burgess HJ, Burns JW, Buvanendran A. Associations between sleep disturbance and chronic pain intensity and function. A test of direct and indirect pathways. [Published online ahead of print March 25, 2019]. Clin J Pain. doi:10.1097/AJP.0000000000000711.
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Sleep Disturbance and Chronic Pain Intensity, Clin J Pain; ePub 2019 Mar 25; Burgess, et al
Dual Receipt of Rx Opioids & Overdose Death, Ann Intern Med; ePub 2019 Mar 12; Moyo, et al
Opioid-Related Mortality in US by Opioid Type, JAMA Netw Open; 2019 Feb 22; Kiang, et al
Disparities in the Prescription of Opioids, JAMA Intern Med; ePub 2019 Feb 11; Friedman, et al
Trends in Pain Prevalence in US Adults, J Pain; ePub 2019 Jan 15; Nahin, et al